SYNJ2BP

SYNJ2BP
Estructuras disponibles
PDB	Búsqueda ortóloga: PDBe RCSB
Lista de codigos id de PDB
	2ENO, 2JIK, 2JIN
Identificadores
Alias	SYNJ2BP, ARIP2, OMP25, synaptojanin 2 binding protein
IDs externos	OMIM: 609411 MGI: 1344347 HomoloGene: 10161 GeneCards: SYNJ2BP
Ontología génica
Función molecular	• GO:0001948, GO:0016582 unión a proteína plasmática; • protein C-terminus binding; • ionotropic glutamate receptor binding;
Componente celular	• componente integral de membrana; • mitochondrial outer membrane; • membrana; • mitocondria; • integral component of mitochondrial outer membrane; • ionotropic glutamate receptor complex; • basolateral plasma membrane; • unión celular; • Unión neuromuscular; • proyección neuronal; • postsynaptic density membrane;
Proceso biológico	• negative regulation of endothelial cell migration; • negative regulation of angiogenesis; • regulation of Notch signaling pathway; • negative regulation of endothelial cell proliferation; • negative regulation of sprouting angiogenesis; • negative regulation of ERK1 and ERK2 cascade; • Hipótesis de la señal; • Rho protein signal transduction; • regulation of endocytosis; • intracellular distribution of mitochondria; • transmisión sináptica química; • receptor clustering; • establishment or maintenance of epithelial cell apical/basal polarity; • receptor localization to synapse; • cell-cell adhesion;
	Fuentes: Amigo / QuickGO
Ortólogos
	55333
	24071
	ENSG00000213463
	ENSMUSG00000090935
	P57105
	Q9D6K5
	NM_018373
	NM_025292; NM_001309814
	NP_060843
	NP_001296743; NP_079568
	Wikidata
Ver/Editar Humano	Ver/Editar Ratón

La proteína de unión a sinaptojanina-2 es una proteína que en humanos está codificada por el gen SYNJ2BP.^[3]^[4]

Interacciones

Se ha demostrado que SYNJ2BP interactúa con:

ACVR2A.^[5]^[3]
ACVR2B.^[3]
LRP1.^[6]
LRP2.^[6]

Véase también

Referencias

↑ «Human PubMed Reference:».
↑ «Mouse PubMed Reference:».
↑ ^a ^b ^c Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway | journal = The Journal of Biological Chemistry | volume = 277 | issue = 21 | pages = 19008–18 | date = May 2002
↑ «Entrez Gene: SYNJ2BP synaptojanin 2 binding protein».
↑ Novel factors in regulation of activin signaling | journal = Molecular and Cellular Endocrinology | volume = 225 | issue = 1–2 | pages = 1–8 | date = Oct 2004.
↑ ^a ^b «Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction». The Journal of Biological Chemistry 275 (33): 25616-24. Aug 2000. PMID 10827173.

Enlaces externos

Esta obra contiene una traducción derivada de «SYNJ2BP» de Wikipedia en inglés, concretamente de esta versión del 4 de marzo de 2023, publicada por sus editores bajo la Licencia de documentación libre de GNU y la Licencia Creative Commons Atribución-CompartirIgual 4.0 Internacional.

Datos: Q18041773

[1] «Human PubMed Reference:».

[2] «Mouse PubMed Reference:».

[pmid11882656-3] Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway | journal = The Journal of Biological Chemistry | volume = 277 | issue = 21 | pages = 19008–18 | date = May 2002

[entrez-4] «Entrez Gene: SYNJ2BP synaptojanin 2 binding protein».

[pmid15451561-5] Novel factors in regulation of activin signaling | journal = Molecular and Cellular Endocrinology | volume = 225 | issue = 1–2 | pages = 1–8 | date = Oct 2004.

[pmid10827173-6] «Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction». The Journal of Biological Chemistry 275 (33): 25616-24. Aug 2000. PMID 10827173.

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